«Published at the World Wide Web of INTERNET on March 18th 2001.»
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A NEW NONLINEAR DNA MODEL

L. Trujillo1, M. Martín1 and J. A. González2
1Laboratorio de Física y Química Computacional, Centro de Resonancia Magnética
Escuela de Física, Facultad de Ciencias
Universidad Central de Venezuela
2Laboratorio de Física Computacional, Centro de Física
Instituto Venezolano de Investigaciones Científicas
Postal Address: Apartado Postal 47586, Caracas 1041-A, Venezuela
mmartin@fisica.ciens.ucv.ve


[Poster presentation, American Physical Society Centennial Meeting, March 1999, Atlanta, Georgia, USA]


Abstract

The torsional dynamics of DNA can be described by nonlinear models, predicting solitonic open states related to replication and transcription processes. In particular, the Yakushevich model yields solitonic solutions with appropriate topological properties to describe those processes. In the present work, we developed a model that combines the dynamical aspects of both Yakushevich and Yomosa models, treating the stacking interaction between adjacent bases in a nonlinear way. By doing so, both transversal and longitudinal interactions are treated on the same foot. Stable solitonic solutions, energies and its dynamics were obtained.



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References

  1. Yomosa, S., , Physical Review A 27 (1983) 2120.

  2. Yakushevich, L. V., , Physics Letters A 136 (1989) 413.

  3. González and M. Martín, , Physics Letters A 191 (1994) 409.

[Web page manteined by Prof. Rafael Martín, updated on march 18th, 2001]


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